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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADAM12
All Species:
16.36
Human Site:
S830
Identified Species:
36
UniProt:
O43184
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O43184
NP_003465.3
909
99542
S830
H
R
A
P
R
A
P
S
V
P
A
R
P
L
P
Chimpanzee
Pan troglodytes
XP_508106
914
100282
S835
H
R
A
P
R
A
P
S
V
P
A
R
P
L
P
Rhesus Macaque
Macaca mulatta
XP_001087980
909
99411
S830
H
R
A
P
R
A
P
S
V
P
A
R
P
L
P
Dog
Lupus familis
XP_546274
909
99674
S828
S
S
R
R
P
P
P
S
R
P
V
P
P
A
P
Cat
Felis silvestris
Mouse
Mus musculus
Q61824
903
98582
S826
H
Q
T
P
R
A
P
S
G
P
A
R
P
L
P
Rat
Rattus norvegicus
Q9QYV0
816
88034
P744
Y
R
A
A
Q
S
G
P
P
E
R
P
G
P
P
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507222
856
93750
S774
L
A
R
R
P
P
P
S
R
P
V
P
P
V
P
Chicken
Gallus gallus
NP_001136322
922
101009
A843
P
Q
P
P
C
H
Q
A
G
P
E
R
P
L
P
Frog
Xenopus laevis
O42596
935
104143
H838
R
R
S
N
G
L
S
H
S
W
S
E
R
I
P
Zebra Danio
Brachydanio rerio
XP_001921148
773
83366
I701
A
C
H
N
V
C
R
I
A
M
A
F
E
K
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
NP_999635
1023
111059
F903
H
S
S
A
K
P
Q
F
R
L
P
P
P
I
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
95.3
94.8
43.7
N.A.
80.3
35.5
N.A.
43.3
71.5
28.3
56.7
N.A.
N.A.
N.A.
N.A.
35.8
Protein Similarity:
100
95.9
97.1
59.4
N.A.
88.1
50.3
N.A.
58
82.4
44.4
65.2
N.A.
N.A.
N.A.
N.A.
51.2
P-Site Identity:
100
100
100
33.3
N.A.
80
20
N.A.
33.3
40
13.3
13.3
N.A.
N.A.
N.A.
N.A.
13.3
P-Site Similarity:
100
100
100
33.3
N.A.
86.6
40
N.A.
40
53.3
33.3
13.3
N.A.
N.A.
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
10
37
19
0
37
0
10
10
0
46
0
0
10
0
% A
% Cys:
0
10
0
0
10
10
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
10
10
10
10
0
10
% E
% Phe:
0
0
0
0
0
0
0
10
0
0
0
10
0
0
0
% F
% Gly:
0
0
0
0
10
0
10
0
19
0
0
0
10
0
0
% G
% His:
46
0
10
0
0
10
0
10
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
10
0
0
0
0
0
19
0
% I
% Lys:
0
0
0
0
10
0
0
0
0
0
0
0
0
10
0
% K
% Leu:
10
0
0
0
0
10
0
0
0
10
0
0
0
46
0
% L
% Met:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% M
% Asn:
0
0
0
19
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
10
0
10
46
19
28
55
10
10
64
10
37
73
10
91
% P
% Gln:
0
19
0
0
10
0
19
0
0
0
0
0
0
0
0
% Q
% Arg:
10
46
19
19
37
0
10
0
28
0
10
46
10
0
0
% R
% Ser:
10
19
19
0
0
10
10
55
10
0
10
0
0
0
0
% S
% Thr:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
0
0
0
0
10
0
0
0
28
0
19
0
0
10
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
10
0
0
0
0
0
% W
% Tyr:
10
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _